Salicylate Toxicity from Ingestion and Continued Dermal Absorption

نویسندگان

  • Rachel L. Chin
  • Kent R. Olson
  • Delia Dempsey
چکیده

Rachel L. Chin, MD*, Kent R. Olson, MD**, Delia Dempsey, MS, MD*** *Professor of Clinical Medicine, University of California, San Francisco School of Medicine. San Francisco General Hospital, SF, CA **Medical Director, San Francisco Bay Area Regional Poison Control Center, Associate Clinical Professor of Medicine, University of California, San Francisco, SF, CA ***Assistant Adjunct Professor of Pediatrics and Clinical Pharmacology and Toxicology, California Poison Control System, University of California, San Francisco, SF, CA. Correspondence: Rachel L. Chin MD, Department of Emergency Services, San Francisco General Hospital, San Francisco, CA 94110. [email protected]

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Salicylate Toxicity from Genital Exposure to a Methylsalicylate-Containing Rubefacient

Methylsalicylate-containing rubefacients have been reported to cause salicylate poisoning after ingestion, topical application to abnormal skin, and inappropriate topical application to normal skin. Many over-the-counter products contain methylsalicylate. Topical salicylates rarely produce systemic toxicity when used appropriately; however, methylsaliclyate can be absorbed through intact skin. ...

متن کامل

Measuring plasma salicylate concentrations in all patients with drug overdose or altered consciousness: is it necessary?

BACKGROUND Salicylate self poisoning is potentially fatal. Plasma salicylate concentrations can be used to guide management when taken in the context of clinical features of toxicity and acid base status. Previous studies in the USA and Hong Kong have shown that routine measurement of plasma salicylate concentrations in all overdose patients is inappropriate, but there have been no previous stu...

متن کامل

Salicylate toxicity from ingestion of traditional massage oil.

A 16-month-old child developed a brief generalised tonic-clonic fitting episode and vomiting at home, after accidental ingestion of traditional massage oil. As the patient presented with clinical features of salicylate toxicity, appropriate management was instituted. He was admitted to the intensive care unit for multiorgan support. The child was discharged well 1 week after the incident...

متن کامل

Carbofuran occupational dermal toxicity, exposure and risk assessment†

BACKGROUND Carbofuran is a carbamate insecticide that inhibits AChE. Although toxic by ingestion in mammals, it has low dermal toxicity, with relatively few confirmed worker illnesses. This risk assessment describes its time of onset, time to peak effect and time to recovery in rats using brain AChE inhibition in acute and 21 day dermal studies; in vitro rat/human relative dermal absorption for...

متن کامل

Tinnitus as a Measure of Salicylate Toxicity in the Overdose Setting

INTRODUCTION The development of tinnitus and/or hearing loss (THL) in patients receiving chronic salicylate therapy has been demonstrated. However, to date, little scientific data validates this relationship in the large single overdose setting. OBJECTIVE To correlate salicylate levels in patients with the subjective complaint of THL, following an acute salicylate overdose. METHODS A retros...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 8  شماره 

صفحات  -

تاریخ انتشار 2007